TREATMENT A-Z

Polynucleotides

What are polynucleotides?

Polynucleotides are short-chain nucleic acids composed of repeating nucleotide units. In aesthetic treatments, they are often used to stimulate collagen production and improve skin quality.

Are polynucleotides a new innovation?

Polynucleotides have been researched for medical applications for several decades, but their use has notably gained attention in the last 10 to 20 years. They were initially explored in the context of gene therapy and regenerative medicine for tissue repair and wound healing.

Over time, their application has broadened to include aesthetic medicine, where they are used for skin rejuvenation and anti-aging treatments.

Are polynucleotides safe?

When administered by a qualified healthcare professional, polynucleotide injections are generally considered safe. However, as with any medical procedure, there may be potential side effects and risks. It is essential to consult with a healthcare provider to determine suitability and address any concerns.

What are the benefits of polynucleotide injections?

Polynucleotide injections can promote collagen synthesis, improve skin elasticity, and enhance skin hydration. They are used to rejuvenate and revitalize the skin, reducing the appearance of wrinkles and fine lines.

They are also of benefit in the treatment of rosacea and acne, reducing inflammation, pigmentation and scarring. Polynucleotides can also help to prime the skin prior to both surgical and non-surgical procedures to aid recovery and enhance outcomes.

What is an example of a polynucleotide?

One example of a polynucleotide used in aesthetic treatments is Polydeoxyribonucleotide (PDRN), derived from salmon DNA. PDRN is known for its skin-regenerating properties and is commonly used in skincare and cosmetic procedures.

How long do polynucleotides take to work?

The time it takes for polynucleotides to take effect may vary among individuals. Some individuals may notice initial improvements in skin texture and hydration within a few weeks of treatment, while optimal results may become apparent after a series of treatments over several months.

What do polynucleotides do in the skin?

Polynucleotides stimulate fibroblasts in the skin, which are responsible for collagen production. This collagen-boosting effect helps improve skin texture, firmness,scarring and overall quality. The anti-inflammatory effects include reducing redness and pigmentation in conditions like acne and rosacea.

What constitutes a polynucleotide?

A polynucleotide is made up of a chain of nucleotide monomers, each composed of a sugar molecule, a phosphate group, and a nitrogenous base. These repeating units form the backbone of the polynucleotide chain.

How do polynucleotides stimulate fibroblasts?

Polynucleotides interact with cell receptors, particularly adenosine receptors, which stimulate fibroblasts' activity. This process leads to increased collagen production and skin rejuvenation.

What do polynucleotides do?

Polynucleotides, when used in aesthetic treatments, stimulate collagen production, improve skin elasticity, and reduce the appearance of fine lines and wrinkles, resulting in smoother and more youthful-looking skin. They can also be used to prime skin prior to surgery or non-surgical procedures such as Broad Band Light, enhancing outcomes and reducing recovery times.

Where are polynucleotides found?

Polynucleotides are naturally found in all living organisms as essential components of DNA and RNA. In aesthetic treatments, they are often derived from sources like salmon DNA.

Is a polynucleotide a protein?

No, polynucleotides are not proteins. They are nucleic acids made up of nucleotide units and play a crucial role in storing and transmitting genetic information.

What is the difference between polynucleotides and fillers?

Polynucleotides and fillers are different types of cosmetic treatments. While polynucleotides stimulate collagen production and improve skin quality, fillers are substances injected to add volume to specific areas of the face or hands.